factor XI deficiency. Other drugs, such as ibuprofen and non-steroidal anti-inflammatory medicines may need to be avoided.

It is important to consult your doctor before using any other medication or herbal remedies.

Inheritance pattern

Factor XI deficiency is usually an inherited condition, caused by a gene alteration. It is an autosomal recessive disorder, meaning that both parents must carry the affected gene in order to pass it to their children. However, some people have bleeding symptoms when it is known that only one of their parents was a carrier.

In some cases, factor XI deficiency can occur spontaneously in people with no known family history.

Symptoms

It is difficult to predict how the condition will affect an individual, as members of the same family can have very different bleeding tendencies. As a general guide, people whose factor XI levels are below 15% of the normal range are more likely to experience a regular bleeding tendency. People whose factor XI levels are above 50% of the normal range may only have bleeding problems during surgery or a dental extraction.

The main symptoms of factor XI deficiency are:

Spontaneous bleeds and bleeding into joints and muscles are not typical of factor XI deficiency.
(published with permission in writing from:http://www.womenbleedtoo.org.uk)




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